Why the study?
Does regional anaesthesia reduce postoperative cognitive dysfunction in elderly patients undergoing major non-cardiac surgery compared to general anaesthesia?
Population
438 patients aged over 60 years undergoing major non-cardiac surgery
Comparison
Regional anaesthesia vs General anaesthesia
Design
RCT, randomly allocated
Follow-up
3 months
Authors
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No long-term POCD advantage for regional over general anesthesia; confirms equivalence and supports individualized selection in elderly non-cardiac surgery.
Does regional anaesthesia reduce postoperative cognitive dysfunction in elderly patients undergoing major non-cardiac surgery compared to general anaesthesia?
Regional anaesthesia does not reduce long-term postoperative cognitive dysfunction compared to general anaesthesia in elderly patients, though it may reduce early POCD and mortality.
Rasmussen et al. (2003) studied this question.
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