Why the study?
Data regarding the incidence of 12-month postoperative cognitive decline following regional or general anaesthesia in older patients undergoing hip fracture surgery remained observational.
Does regional anaesthesia reduce the incidence of 12-month postoperative cognitive decline in older patients undergoing hip fracture surgery compared to general anaesthesia?
Population
950 patients aged ≥ 65 y with hip fractures requiring surgery
Comparison
Regional anaesthesia with no sedation vs general anaesthesia
Design
Multicentre randomised trial substudy
Follow-up
12 months
Authors
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Observational substudy data leave open whether regional anaesthesia reduces 12-month cognitive decline after hip fracture surgery; dedicated RCTs needed.
Does regional anaesthesia reduce the incidence of 12-month postoperative cognitive decline in older patients undergoing hip fracture surgery compared to general anaesthesia?
Regional anaesthesia does not significantly reduce the incidence of 12-month postoperative cognitive decline compared to general anaesthesia in older patients undergoing hip fracture surgery.
Li et al. (2025) studied this question.
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