Cancer history and mortality risk in acute myocardial infarction: Insights from the Japan AMI registry

Figures

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  Fig. 1. Comparison of adjusted Kaplan-Meier curves for clinical outcomes This figure shows one-year Kaplan-Meier curves for each outcome according to the presence or absence of a history of cancer. The solid red line represents the group with a history of cancer, and the solid blue line represents the group without a history of cancer. A) all-cause death; B) Major bleeding; C) CV death, MI, and ischemic stroke; D) CV death; E) non-CV death; F) cancer death. CV = cardiovascular; MI = myocardial infarction. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

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  Fig. 2. Observed risk of events in patients with vs. without cancer This graph shows the adjusted hazard ratio for patients with a history of cancer compared to patients without a history of cancer. Covariates in the multivariable models included age, sex, body weight, ST-elevation MI (STEMI) or non-STEMI, use of anticoagulants, history of cerebrovascular disease, use of primary percutaneous coronary intervention (PCI), trans-radial approach, Killip class ≥ 2, estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m2, and history of previous MI or PCI. HR = hazard ratio; CI = confidence interval; CV = cardiovascular; MI = myocardial infarction.

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  Fig. 3. Observed risk of events in patients with vs. without cancer between < 75 years old and ≥ 75 years old patients This graph shows the adjusted hazard ratio for patients aged < 75 and ≥ 75 with a history of cancer compared to those without a history of cancer. Covariates in the multivariable models included sex, body weight, ST-elevation MI (STEMI) or non-STEMI, use of anticoagulants, history of cerebrovascular disease, use of primary percutaneous coronary intervention (PCI), trans-radial approach, Killip class ≥ 2, estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m2, and history of previous MI or PCI. HR = hazard ratio; CI = confidence interval; CV = cardiovascular; MI = myocardial infarction.

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  Fig. 4. The association of a history of cancer for clinical outcomes across a range of ages This graph shows the adjusted hazard ratio for patients with a history of cancer compared to patients without a history of cancer, when age is used as a continuous variable. The solid line in the middle is the HR, and the upper and lower dotted lines are the upper and lower 95 % CIs, respectively. Covariates in the multivariable models included sex, body weight, ST-elevation MI (STEMI) or non-STEMI, use of anticoagulants, history of cerebrovascular disease, use of primary percutaneous coronary intervention (PCI), trans-radial approach, Killip class ≥ 2, estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m2, and history of previous MI or PCI. A) all-cause death; B) CV death; C) non-CV death. HR = hazard ratio; CV = cardiovascular.