February 1, 2006Journal of Clinical MicrobiologyOpen Access

Emergence of a New Norovirus Genotype II.4 Variant Associated with Global Outbreaks of Gastroenteritis

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Population

Norovirus strains isolated from sporadic and outbreak cases of gastroenteritis between 1997 and 2004 in New…

Design

Other

Authors

RBRowena A. BullThe University of Sydney ETElise TuUNSW Sydney CMChristopher J. McIverSutherland Hospital

Discussion

Member takes

Implication

May prompt inclusion of emerging GII.4 variants in norovirus surveillance; leaves open needs for updated diagnostics and vaccines.

Structured PICO

Population

Norovirus strains isolated from sporadic and outbreak cases of gastroenteritis between 1997 and 2004 in New South Wales, Australia, and subsequently from The Netherlands, Japan, and Taiwan in 2004 and 2005.

Intervention

Nested reverse transcriptase PCR (nRT-PCR) designed to amplify the highly conserved 3' end of the polymerase region and the 5' end of the capsid gene of NoV genogroup II (GII).

Outcome

Identification and phylogenetic analysis of Norovirus genotypes.

A novel Norovirus GII.4 variant (Hunter virus) was identified using a newly designed nRT-PCR and found to be responsible for global outbreaks of gastroenteritis in 2004-2005.

Cite This Study

Bull et al. (2006) studied this question.

synapsesocial.com/papers/6a70091b2163a0a01bc44075 https://doi.org/10.1128/jcm.44.2.327-333.2006

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Emergence of a New Norovirus Genotype II.4 Variant Associated with Global Outbreaks of Gastroenteritis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Emergence of a New Norovirus Genotype II.4 Variant Associated with Global Outbreaks of Gastroenteritis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider