Molecular Epidemiology of Genogroup II-Genotype 4 Noroviruses in the United States between 1994 and 2006
Population
773 norovirus outbreaks reported to the CDC from 1994 to 2006
Design
Other
Authors
Discussion
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Member takes
Implication
GII.4 dominance supports ongoing norovirus surveillance; this Level 5 analysis leaves open drivers of emergence and vaccine implications.
Structured PICO
P
Population
773 norovirus outbreaks reported to the CDC from 1994 to 2006
O
Outcome
Proportion of outbreaks caused by GII.4 strains and genetic variation of the full-length VP1 gene
This study highlights the rapid emergence, displacement, and increasing prevalence of highly virulent GII.4 norovirus strains in the US between 1994 and 2006.
Cite This Study
Zheng et al. (2009) studied this question.