Why the study?
Are specific autoantibodies associated with cardiodepressant activity in patients with dilated cardiomyopathy?
Population
104 patients with dilated cardiomyopathy (DCM)
Design
Cross-sectional
Authors
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Anti-β1- and anti-M2-receptor antibodies associate with cardiodepressant activity in DCM; hypothesis-generating for screening but should not yet change practice.
Are specific autoantibodies associated with cardiodepressant activity in patients with dilated cardiomyopathy?
An ex vivo chick embryo model can successfully screen for cardiodepressant autoantibodies in DCM patients, which are strongly predicted by the presence of anti-beta1- or anti-M2-receptor antibodies.
Akiyasu Baba (2008) studied this question.
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