Why the study?
What clinical factors are associated with a positive D-dimer result in patients evaluated for pulmonary embolism?
What clinical factors are associated with a positive D-dimer result in patients evaluated for pulmonary embolism?
Numerous clinical factors, including age, sex, race, and specific comorbidities, are associated with positive D-dimer results and should be considered before ordering the test to avoid unnecessary radiographic imaging for PE.
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May inform selective D-dimer use in suspected PE; leaves open whether adjusted thresholds reduce unnecessary imaging.
Kabrhel et al. (2010) studied this question.
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