Why the study?
Does antipsychotic medication use and metabolic parameters affect the QTc interval in psychiatric outpatients?
Population
103 psychiatric out-patients across the diagnostic spectrum taking antipsychotic medication for a minimum of…
Design
Cross-sectional
Authors
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May reduce emphasis on metabolic monitoring for QTc in stable outpatients; leaves open prospective assessment of antipsychotic contributions.
Does antipsychotic medication use and metabolic parameters affect the QTc interval in psychiatric outpatients?
QTc prolongation is uncommon in psychiatric outpatients on long-term antipsychotics, and while associated with age, it does not appear related to metabolic parameters.
Mackin et al. (2005) studied this question.