Why the study?
Recent studies have highlighted the importance of inter-organ crosstalk via secretory factors, motivating an overview of exercise-induced adaptations in brown and white adipose tissue and their effects on cardiac health and function.
Exercise promotes beneficial inter-organ crosstalk via adipokines released from adipose tissue, which improve cardiac function and health.
Answers are grounded in this paper and cite their sources.
Exercise-induced adipokine release may link adipose tissue to cardiac protection; leaves open specific mediators and clinical translation.
Exercise leads to numerous beneficial whole-body effects and can protect against the development of obesity, cardiometabolic, and neurodegenerative diseases. Recent studies have highlighted the importance of inter-organ crosstalk with a focus on secretory factors that mediate communication among organs, including adipose tissue and the heart. Studies investigating the effects of exercise on brown adipose tissue (BAT) and white adipose tissue (WAT) demonstrated that adipokines are released in response to exercise and act on the heart to decrease inflammation, alter gene expression, increase angiogenesis, and improve cardiac function. This review discusses the exercise-induced adaptations to BAT and WAT and how these adaptations affect heart health and function, while highlighting the importance of tissue crosstalk.
No takes yet. Share an insight, caveat, or question.
Blackwell et al. (2022) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: