November 1, 1979International Journal of Gynecology & Obstetrics
Oral Contraceptive Hypertension and Thromboembolism
Why the study?
Do oral contraceptives increase the risk of hypertension, atherogenesis, and thromboembolic events in women?
Population
Women using oral contraceptives, with specific mention of high-risk groups including those with a history of…
Design
Review
Authors
Discussion
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Implication
Supports caution with oral contraceptives in women with cardiovascular risks; leaves open precise event rates pending prospective studies.
Structured PICO
Do oral contraceptives increase the risk of hypertension, atherogenesis, and thromboembolic events in women?
P
Population
Women using oral contraceptives, with specific mention of high-risk groups including those with a history of hypertension, gestational hypertension, family history of hypertension, blacks, diabetics, and women with renal disease
I
Intervention
Oral contraceptives
O
Outcome
Worsening of major atherogenic cardiovascular risk factors, severe hypertensive episodes, massive hypertriglyceridemia, and thromboembolic eventssafety
Oral contraceptive use requires careful monitoring for cardiovascular and thromboembolic risks, and is considered imprudent for women with a history of hypertension.
Cite This Study
William B. Kannel (1979) studied this question.