Why the study?
Does the number of concomitant drugs affect the stability of long-term anticoagulant therapy?
Population
277 patients on long-term anticoagulant therapy
Design
Cohort
Authors
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May warrant closer monitoring in anticoagulated patients with polypharmacy; leaves open causal effects and intervention benefits.
Does the number of concomitant drugs affect the stability of long-term anticoagulant therapy?
The stability of long-term anticoagulant therapy is negatively impacted by the number of concomitant medications, highlighting the need for closer monitoring in patients with polypharmacy.
Williams et al. (1976) studied this question.
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