Why the study?
Does a low-dose intravenous vitamin K titration protocol safely and effectively reverse warfarin for early hip fracture surgery?
Does a low-dose intravenous vitamin K titration protocol safely and effectively reverse warfarin for early hip fracture surgery?
A low-dose intravenous vitamin K protocol safely and effectively reverses warfarin within 18 hours, facilitating early hip fracture surgery without increasing thromboembolic risk.
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May allow earlier hip fracture surgery in low-risk patients; hypothesis-generating and requires RCT confirmation before practice change.
Moores et al. (2015) studied this question.
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