Why the study?
Suitable biomarkers for risk assessment of depression have not been established, although cytokine alterations are assumed to be involved in the pathophysiology and severity of major depressive disorder.
Are serum adiponectin and IL-8 levels altered in patients with major depressive disorder compared to healthy controls?
Population
63 MDD patients and 94 age-sex matched healthy controls in Bangladesh
Comparison
MDD patients vs healthy controls
Design
Case-control study
Authors
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Cytokine alterations may associate with MDD; hypothesis-generating for biomarkers, needs prospective validation.
Are serum adiponectin and IL-8 levels altered in patients with major depressive disorder compared to healthy controls?
Serum adiponectin and IL-8 levels are significantly altered in patients with major depressive disorder, suggesting potential utility as early risk assessment biomarkers.
Islam et al. (2022) studied this question.
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