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September 7, 2013Heart

Global left ventricular longitudinal systolic strain as a major predictor of cardiovascular events in patients with atrial fibrillation

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Why the study?

Does global left ventricular longitudinal systolic strain (GLS) predict cardiovascular events better than LVEF and Sa in patients with persistent atrial fibrillation?

Population

196 patients with persistent atrial fibrillation referred for echocardiographic examination

Comparison

Global left ventricular longitudinal systolic… vs Left ventricular ejection fraction and systolic…

Design

Cohort

Follow-up

average 21 ± 10 months

Authors

HSHo‐Ming SuCardiac ImagingTLTsung‐Hsien LinInterventional / Structural CardiologyPHPo‐Chao HsuInterventional Cardiology

Discussion

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Implication

GLS may enhance prognostication in persistent AF; hypothesis-generating and requires prospective validation before practice change.

Structured PICO

Does global left ventricular longitudinal systolic strain (GLS) predict cardiovascular events better than LVEF and Sa in patients with persistent atrial fibrillation?

P
Population
196 patients with persistent atrial fibrillation referred for echocardiographic examination
I
Intervention
Global left ventricular longitudinal systolic strain (GLS) measurement
C
Comparator
Left ventricular ejection fraction (LVEF) and systolic mitral annulus velocity (Sa)
O
Outcome
Composite of cardiovascular events (cardiovascular death, non-fatal stroke, and hospitalisation for heart failure)composite

Global longitudinal strain is a stronger predictor of adverse cardiovascular events than LVEF and Sa in patients with persistent atrial fibrillation.

Cite This Study

Su et al. (2013) studied this question.

synapsesocial.com/papers/6a701e5131a3df82432864adhttps://doi.org/10.1136/heartjnl-2013-304561

Topics

Atrial fibrillationPersistent AF managementHeart failureHeart failure hospitalizationHFrEF treatment
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Also Consider

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  1. 1Predictors of mortality and morbidity in patients with chronic heart failure2005 · 977 citations
  2. 2Doppler Tissue Imaging: A Noninvasive Technique for Evaluation of Left Ventricular Relaxation and Estimation of Filling Pressures1997 · 3,041 citations
  3. 3Ischaemic cardiovascular mortality in patients with non-valvular atrial fibrillation according to CHADS2 score2011 · 22 citations