November 1, 1985Pacing and Clinical Electrophysiology
A Time‐Related Study of the Hemodynamic Benefit of Atrioventricular Synchronous Pacing Evaluated by Doppler Echocardiography
Why the study?
Does DDD pacing improve stroke volume compared to VVI pacing in patients equipped with pacemakers?
Population
13 patients equipped with DDD pacemakers
Comparison
DDD pacing evaluated at 1, 3, 6, and 12 months… vs VVI pacing
Design
Cohort
Follow-up
12 months
Authors
Discussion
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Implication
DDD pacing was associated with higher stroke volume than VVI; hypothesis-generating for AV optimization and requires randomized outcome trials.
Structured PICO
Does DDD pacing improve stroke volume compared to VVI pacing in patients equipped with pacemakers?
P
Population
13 patients equipped with DDD pacemakers
I
Intervention
DDD pacing (atrioventricular synchronous pacing) evaluated at 1, 3, 6, and 12 months, and at seven AV intervals (75-250 ms)
C
Comparator
VVI pacing
O
Outcome
Stroke volume (SV) estimated by Doppler echocardiographysurrogate
DDD pacing provides both short- and long-term hemodynamic benefits with increased stroke volume compared to VVI pacing, which can be optimized by individualizing the AV interval using Doppler echocardiography.
Cite This Study
Færestrand et al. (1985) studied this question.