What question did this study set out to answer?

To determine whether beat-to-beat variability in stroke volume during VVI pacing predicts the degree of hemodynamic improvement achieved with DDD pacing.

August 1, 1993Pacing and Clinical Electrophysiology

Beat‐to‐Beat Variability in Stroke Volume During VVI Pacing as Predictor of Hemodynamic Benefit from DDD Pacing

View Full Paper

Ask AI

Bookmark

Why the study?

Does beat-to-beat variability in stroke volume during VVI pacing predict hemodynamic benefit from DDD pacing in patients with AV block?

Population

20 patients (mean age 54 +/- 9 years) with DDD pacemakers implanted due to AV block.

Comparison

DDD pacing vs VVI pacing

Design

Cross-sectional

Authors

ADAthanase DritsasHammersmith Hospital JJJayshree JoshiTrillium Health Centre SWS C WebbUniversity of Ulster

Discussion

Member takes

Implication

Stroke volume variability during VVI pacing was associated with hemodynamic benefit from DDD pacing; hypothesis-generating in cross-sectional data and requires prospective confirmation.

Key Points

To determine whether beat-to-beat variability in stroke volume during VVI pacing predicts the degree of hemodynamic improvement achieved with DDD pacing.
Conducted Doppler echocardiographic recordings of left ventricular systolic and diastolic flow during both VVI and DDD pacing modes.
Evaluated 20 patients (mean age 54 ± 9 years) with implanted dual-chamber pacemakers due to complete atrioventricular block.
Stroke volume increased by 19% ± 10% overall from VVI to DDD pacing (P < 0.01), with a greater increase in patients with an E/A ratio < 1 (29% ± 9%) compared to E/A > 1 (10% ± 9%, P < 0.001).
Beat-to-beat variability in stroke volume was significantly higher during VVI pacing (13% ± 8%) compared to DDD pacing (4% ± 1%, P < 0.001), particularly in patients with E/A < 1 (19% ± 6% vs 8% ± 4%, P < 0.001).
Stroke volume variability during VVI pacing correlated strongly with the relative increase in stroke volume from VVI to DDD (r = 0.89, P < 0.001) and inversely with the E/A ratio (r = -0.71, P < 0.001).

Structured PICO

Does beat-to-beat variability in stroke volume during VVI pacing predict hemodynamic benefit from DDD pacing in patients with AV block?

Population

20 patients (mean age 54 +/- 9 years) with DDD pacemakers implanted due to AV block.

Intervention

DDD pacing

Comparator

VVI pacing

Outcome

Change in stroke volume (SV) from VVI to DDD pacing and beat-to-beat variability in SVsurrogate

In patients with AV block, large beat-to-beat variations in stroke volume during VVI pacing predict a greater hemodynamic benefit when switching to DDD pacing.

Cite This Study

Dritsas et al. (1993) studied this question.

synapsesocial.com/papers/6a7137ee35aa2c282ce286d9 https://doi.org/10.1111/j.1540-8159.1993.tb01042.x

Topics

Mitral valve intervention Echocardiography Tricuspid regurgitation

View Full Paper

Ask AI

Bookmark

Implication

Stroke volume variability during VVI pacing was associated with hemodynamic benefit from DDD pacing; hypothesis-generating in cross-sectional data and requires prospective confirmation.

Beat‐to‐Beat Variability in Stroke Volume During VVI Pacing as Predictor of Hemodynamic Benefit from DDD Pacing

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Beat‐to‐Beat Variability in Stroke Volume During VVI Pacing as Predictor of Hemodynamic Benefit from DDD Pacing

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider