Why the study?
Is diastolic dysfunction in type 2 diabetes mellitus associated with myocardial triglyceride content or impaired myocardial perfusion reserve?
Population
58 subjects: 42 patients with type 2 diabetes mellitus, preserved systolic function, and without clinically…
Comparison
Cardiac magnetic resonance with strain-encoded… vs Age-matched healthy volunteers
Design
Cross-sectional
Authors
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Myocardial steatosis may mark early diastolic dysfunction in T2DM; hypothesis-generating and requires prospective validation before clinical adoption.
Is diastolic dysfunction in type 2 diabetes mellitus associated with myocardial triglyceride content or impaired myocardial perfusion reserve?
Myocardial steatosis may be an early marker of diabetic heart disease that triggers subclinical diastolic dysfunction independently of myocardial perfusion reserve.
Korosoglou et al. (2011) studied this question.
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