January 29, 2019Journal of BiomechanicsOpen Access

Non-identifiability of parameters for a class of shear-thinning rheological models, with implications for haematological fluid dynamics

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Why the study?

Shear-thinning complex fluid models are widely applied in hemodynamics, but uncertainty remains regarding naming conventions and inferring model parameters by fitting to rheology experiments.

Design

Computational simulation and refitting study

Authors

MGMeurig T. GallagherUniversity of Birmingham RWRichard A. J. WainUniversity of Lancashire SDSonia Dari

Discussion

Member takes

Implication

Naming inconsistencies in shear-thinning models risk misapplication in hemodynamic simulations; leaves open the need for standardized nomenclature.

Structured PICO

Population

Computational models of shear-thinning complex fluids (Bird, Carreau, Cross, and Yasuda models) used in hemodynamics

Intervention

Parameter inference by fitting to rheology experiments and synthetic data

Outcome

Parameter identifiability and flow profile prediction

Parameter identifiability is an intrinsic problem in commonly used shear-thinning rheological models for hemodynamics, meaning fitted parameters cannot reliably infer physical fluid properties or flow behaviors.

Cite This Study

Gallagher et al. (2019) studied this question.

synapsesocial.com/papers/6a701f465d37378ac1dd2f75 https://doi.org/10.1016/j.jbiomech.2019.01.036

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Implication

Naming inconsistencies in shear-thinning models risk misapplication in hemodynamic simulations; leaves open the need for standardized nomenclature.

Non-identifiability of parameters for a class of shear-thinning rheological models, with implications for haematological fluid dynamics

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Non-identifiability of parameters for a class of shear-thinning rheological models, with implications for haematological fluid dynamics

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider