What question did this study set out to answer?

To identify anthropometric variables in childhood that correlate with unfavorable changes in lipid and apolipoprotein profiles linked to cardiovascular disease risk.

September 1, 1994Acta Paediatrica

Waist measurement correlates to a potentially atherogenic lipoprotein profile in obese 12–14–year‐old children

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Why the study?

Does waist measurement correlate with an atherogenic lipoprotein profile in obese 12-14-year-old children?

Key Points

To identify anthropometric variables in childhood that correlate with unfavorable changes in lipid and apolipoprotein profiles linked to cardiovascular disease risk.
Recruited 61 obese adolescents (29 aged 14 and 32 aged 12) through a school screening program.
Evaluated anthropometric variables against blood pressure, lipids, and apolipoproteins using analysis of covariance and partial correlations adjusted for puberty, sex, and screening group.
Waist circumference significantly correlated inversely with HDL cholesterol (r = -0.08, p < 0.05) and positively with triglycerides (r = +0.24, p < 0.01).
Waist-to-hip ratio significantly correlated with HDL cholesterol (r = -0.10, p < 0.01) and triglycerides (r = +0.22, p < 0.01), while BMI correlated with triglycerides (r = +0.25, p < 0.001) and diastolic blood pressure (r = +0.08, p < 0.05).
Partial regression coefficients for waist circumference against apolipoprotein B (r = +0.07) and the apolipoprotein B:A-I ratio (r = +0.06) were comparable in strength to those observed for waist-to-hip ratio.

Structured PICO

Does waist measurement correlate with an atherogenic lipoprotein profile in obese 12-14-year-old children?

Population

61 obese children (29 aged 14 years, 32 aged 12 years) recruited from a school screening programme.

Intervention

Anthropometric measurements (waist circumference, waist:hip ratio, BMI)

Outcome

Correlation of anthropometric variables with blood pressure, apolipoprotein, and lipid concentrationssurrogate

Waist measurement is a convenient anthropometric indicator that correlates with an atherogenic lipoprotein profile in obese 12-14-year-old children.

Discussion

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Implication

May support waist circumference as dyslipidemia marker in obese adolescents; hypothesis-generating, requires prospective validation.

Cite This Study

Flodmark et al. (1994) studied this question.

synapsesocial.com/papers/6a701f80b5c1fe5ca9dfa9ff https://doi.org/10.1111/j.1651-2227.1994.tb13177.x

Topics

Women and heart disease

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Waist measurement correlates to a potentially atherogenic lipoprotein profile in obese 12–14–year‐old children

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Waist measurement correlates to a potentially atherogenic lipoprotein profile in obese 12–14–year‐old children

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider