Plasma and renal clearance of iohexol–a study on the reproducibility of a method for the glomerular filtration rate

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Population

12 healthy subjects

Design

Other

Authors

Discussion

Supports iohexol clearance reproducibility for GFR research; leaves open standardization and clinical validation in larger cohorts.

Population

12 healthy subjects

Intervention

Triplicate constant-rate infusions of iohexol

Outcome

Reproducibility of iohexol clearance (renal and plasma) as a determination of glomerular filtration ratesurrogate

Iohexol clearance via constant-rate infusion is a simple and reproducible method for determining glomerular filtration rate.

Arvidsson et al. (1990) studied this question.

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