What question did this study set out to answer?

To evaluate clinical outcomes of isolated undersized mitral annuloplasty in non-ischemic dilated cardiomyopathy and assess whether a preoperative coaptation depth ≥11 mm reliably predicts persistent mitral regurgitation.

January 1, 2008Circulation JournalOpen Access

Isolated Undersized Mitral Annuloplasty for Functional Mitral Regurgitation in Non-Ischemic Dilated Cardiomyopathy Reconsideration of the Relationship Between Preoperative Coaptation Depth and Persistent Mitral Regurgitation

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Why the study?

Does isolated undersized mitral annuloplasty improve functional MR and symptoms in patients with non-ischemic dilated cardiomyopathy?

Population

6 patients with severe functional mitral regurgitation in non-ischemic dilated cardiomyopathy, mean age 61…

Design

Case_series

Follow-up

mean 2.2+/-1.9 years, 1.9+/-1.7 years

Authors

TMTakashi MiuraNagano Prefecture Forestry Research Center KEKiyoyuki EishiNagasaki University SYShiro YamachikaInoue Hospital

Discussion

Member takes

Implication

Suggests benefit from isolated annuloplasty in non-ischemic DCM; hypothesis-generating and should not yet change practice.

Key Points

To evaluate clinical outcomes of isolated undersized mitral annuloplasty in non-ischemic dilated cardiomyopathy and assess whether a preoperative coaptation depth ≥11 mm reliably predicts persistent mitral regurgitation.
Retrospective case series of 6 patients (mean age, 61 years) with severe functional mitral regurgitation secondary to non-ischemic dilated cardiomyopathy who underwent isolated undersized mitral annuloplasty.
Clinical follow-up averaged 2.2 ± 1.9 years, and echocardiographic evaluation was performed at a mean follow-up of 1.9 ± 1.7 years.
In-hospital mortality was 0%, and New York Heart Association functional class improved from 3.3 ± 0.5 preoperatively to 2.2 ± 0.4 postoperatively (p = 0.0016).
Mitral regurgitation grade decreased significantly from 4.0 ± 0.0 at baseline to 1.0 ± 0.6 at follow-up (p < 0.001).
Among 5 patients with a baseline coaptation depth ≥11 mm, 4 experienced reduction of functional mitral regurgitation to mild or less.

Structured PICO

Does isolated undersized mitral annuloplasty improve functional MR and symptoms in patients with non-ischemic dilated cardiomyopathy?

Population

6 patients with severe functional mitral regurgitation in non-ischemic dilated cardiomyopathy, mean age 61 years.

Intervention

Isolated undersized mitral annuloplasty

Outcome

New York Heart Association (NYHA) functional class and mitral regurgitation (MR) gradesurrogate

Isolated undersized mitral annuloplasty improves clinical symptoms and functional MR in non-ischemic DCM, suggesting that preoperative coaptation depth >=11 mm does not always predict recurrent MR.

Cite This Study

Miura et al. (2008) studied this question.

synapsesocial.com/papers/6a701fb9a528af2d65c35896 https://doi.org/10.1253/circj.cj-07-0983

Topics

Mitral valve intervention

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January 1, 2008Circulation JournalOpen Access

Isolated Undersized Mitral Annuloplasty for Functional Mitral Regurgitation in Non-Ischemic Dilated Cardiomyopathy Reconsideration of the Relationship Between Preoperative Coaptation Depth and Persistent Mitral Regurgitation

View Full Paper

Ask AI

Bookmark

Why the study?

Does isolated undersized mitral annuloplasty improve functional MR and symptoms in patients with non-ischemic dilated cardiomyopathy?

Population

6 patients with severe functional mitral regurgitation in non-ischemic dilated cardiomyopathy, mean age 61…

Design

Case_series

Follow-up

mean 2.2+/-1.9 years, 1.9+/-1.7 years

Authors

TMTakashi MiuraNagano Prefecture Forestry Research Center KEKiyoyuki EishiNagasaki University SYShiro YamachikaInoue Hospital

Discussion

Member takes

Implication

Suggests benefit from isolated annuloplasty in non-ischemic DCM; hypothesis-generating and should not yet change practice.

Key Points

To evaluate clinical outcomes of isolated undersized mitral annuloplasty in non-ischemic dilated cardiomyopathy and assess whether a preoperative coaptation depth ≥11 mm reliably predicts persistent mitral regurgitation.
Retrospective case series of 6 patients (mean age, 61 years) with severe functional mitral regurgitation secondary to non-ischemic dilated cardiomyopathy who underwent isolated undersized mitral annuloplasty.
Clinical follow-up averaged 2.2 ± 1.9 years, and echocardiographic evaluation was performed at a mean follow-up of 1.9 ± 1.7 years.
In-hospital mortality was 0%, and New York Heart Association functional class improved from 3.3 ± 0.5 preoperatively to 2.2 ± 0.4 postoperatively (p = 0.0016).
Mitral regurgitation grade decreased significantly from 4.0 ± 0.0 at baseline to 1.0 ± 0.6 at follow-up (p < 0.001).
Among 5 patients with a baseline coaptation depth ≥11 mm, 4 experienced reduction of functional mitral regurgitation to mild or less.

Structured PICO

Does isolated undersized mitral annuloplasty improve functional MR and symptoms in patients with non-ischemic dilated cardiomyopathy?

Population

6 patients with severe functional mitral regurgitation in non-ischemic dilated cardiomyopathy, mean age 61 years.

Intervention

Isolated undersized mitral annuloplasty

Outcome

New York Heart Association (NYHA) functional class and mitral regurgitation (MR) gradesurrogate

Isolated undersized mitral annuloplasty improves clinical symptoms and functional MR in non-ischemic DCM, suggesting that preoperative coaptation depth >=11 mm does not always predict recurrent MR.

Cite This Study

Miura et al. (2008) studied this question.

synapsesocial.com/papers/6a701fb9a528af2d65c35896 https://doi.org/10.1253/circj.cj-07-0983

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Mitral valve intervention

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