December 16, 2008Circulation Cardiovascular InterventionsOpen Access

Twenty-Year Evolution of Percutaneous Coronary Intervention and Its Impact on Clinical Outcomes

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Why the study?

Does contemporary PCI compared to balloon-era PTCA improve clinical outcomes in patients undergoing percutaneous revascularization?

Population

8,976 consecutive patients undergoing percutaneous coronary intervention in the multicenter, National Heart…

Comparison

PCI in contemporary eras. vs PCI in the balloon era (1985-1986 PTCA Registry).

Design

Cohort

Follow-up

up to 365 days

Authors

LVLakshmi VenkitachalamPreventive Cardiology KKKevin E. KipPreventive Cardiology FSFaith SelzerBoston University

Discussion

Member takes

Implication

Contemporary PCI was associated with fewer complications than historical PTCA; extends observational trends but leaves causal attribution open.

Structured PICO

Does contemporary PCI compared to balloon-era PTCA improve clinical outcomes in patients undergoing percutaneous revascularization?

Population

8,976 consecutive patients undergoing percutaneous coronary intervention (PCI) in the multicenter, National Heart, Lung, and Blood Institute-sponsored 1985-1986 PTCA and 1997-2006 Dynamic Registries waves.

Intervention

PCI in contemporary eras (wave 1: 1997-1998, bare-metal stents; wave 2: 1999, uniform use of stents; wave 3: 2001-2002, brachytherapy; waves 4 and 5: 2004-2006, drug-eluting stents).

Comparator

PCI in the balloon era (1985-1986 PTCA Registry).

Outcome

In-hospital rates of myocardial infarction and emergency coronary artery bypass surgery, and risk for repeat revascularization (31 to 365 days after index PCI).hard clinical

Over a 20-year period, PCI has evolved to treat older and more comorbid patients while achieving significantly lower rates of in-hospital complications and repeat revascularization.

Cite This Study

Venkitachalam et al. (2008) studied this question.

synapsesocial.com/papers/6a70201afebe604dd708ed80 https://doi.org/10.1161/circinterventions.108.825323

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Implication

Contemporary PCI was associated with fewer complications than historical PTCA; extends observational trends but leaves causal attribution open.

Twenty-Year Evolution of Percutaneous Coronary Intervention and Its Impact on Clinical Outcomes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Twenty-Year Evolution of Percutaneous Coronary Intervention and Its Impact on Clinical Outcomes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider