Why the study?
This comment was written in response to a recent article to discuss the nonreplicative joining of viral RNA fragments.
Design
Formal Comment
This is the authors' abstract. We don't add key points for this paper.
In response to a recent article, this Formal Comment discusses nonreplicative joining of fragments of viral RNAs, a class of reactions which might be widespread in nature, contributing to conservation and evolution not only of viruses but of cellular organisms as well.
Nonreplicative viral RNA joining may drive evolution across domains; leaves open its prevalence and mechanisms in natural populations.
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Vadim I. Agol (2023) studied this question.
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