Why the study?
The full phenotypic spectrum of cardiovascular complications in hypermobile Ehlers-Danlos syndrome had not been studied following updated nosology and diagnostic criteria.
What is the incidence and spectrum of cardiovascular involvement in patients with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders?
Population
258 patients diagnosed with hEDS or HSD referred for joint hypermobility
Design
Retrospective review
Authors
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Supports echocardiography in symptomatic hEDS/HSD adults; leaves open progression risk and optimal surveillance intervals.
What is the incidence and spectrum of cardiovascular involvement in patients with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders?
Cardiovascular manifestations in adults with hEDS/HSD are typically mild and include mitral valve prolapse and aortic dilatation, though rare extra-aortic arterial involvement such as cervical artery dissection and spontaneous coronary artery dissection can occur.
Rashed et al. (2022) studied this question.
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