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Sex-specific obesity strategies merit consideration in practice; leaves open mechanistic questions on neural-inflammatory pathways for targeted trials.
Obesity along with its comorbidities is escalating rapidly in epidemic fashion worldwide. Sex differences exist in the etiopathogenesis of obesity-mediated diseases, which is primarily mediated by the distribution of adipose tissue and alterations in the neural regulation. In this review, we have emphasized the role of gender in the development of obesity, and its alterations in the neural and its associated inflammatory pathways.
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Pal et al. (2016) studied this question.
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