Why the study?
Does acute hypercortisolemia alter lipolysis in subcutaneous adipose tissue and the whole body in healthy subjects?
Does acute hypercortisolemia alter lipolysis in subcutaneous adipose tissue and the whole body in healthy subjects?
Acute hypercortisolemia increases systemic lipolysis while decreasing intracellular lipolysis in subcutaneous abdominal adipose tissue, potentially explaining central fat deposition.
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No practice change warranted in hypercortisolemia; leaves open tissue-specific lipolysis as a mechanism for central adiposity.
Samra et al. (1998) studied this question.
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