Why the study?
Does cortisol increase lipoprotein lipase activity in human adipose tissue in vitro?
Population
Human adipose tissue (in vitro tissue incubation technique)
Comparison
Cortisol added to control medium containing… vs Control medium containing insulin without cortisol
Design
Preclinical
Follow-up
5 days of incubation (2 days of exposure)
Authors
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May influence adipose lipid handling; leaves open human applicability given animal model data.
Does cortisol increase lipoprotein lipase activity in human adipose tissue in vitro?
Cortisol, in the presence of insulin, markedly stimulates lipoprotein lipase activity in human adipose tissue via increased mRNA levels and posttranslational regulation.
Ottosson et al. (1994) studied this question.
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