Population
Male Sprague-Dawley rats and isolated rat adipocytes
Comparison
Dexamethasone vs Sham-injected controls and untreated control…
Design
Preclinical
Follow-up
10 days (in vivo), 24 hours (in vitro)
Authors
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Does not support changes in glucocorticoid use; leaves open human relevance of adipocyte LPL suppression.
Dexamethasone decreases adipocyte lipoprotein lipase mRNA levels, synthetic rate, and activity both in vitro and in vivo.
Ong et al. (1992) studied this question.
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