Why the study?
Does protein restriction after weaning alter cardiac autonomic balance in rats?
Population
30 rats after weaning (n=16 control, n=14 malnourished)
Comparison
6% protein diet vs 15% protein diet (control)
Design
Preclinical
Authors
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Suggests autonomic imbalance as a malnutrition pathway in rats; leaves open translation to human cardiovascular risk.
Does protein restriction after weaning alter cardiac autonomic balance in rats?
Protein malnutrition after weaning in rats increases sympathetic activity and reduces vagal activity to the heart, providing insight into the pathophysiology of associated metabolic and cardiovascular diseases.
Martins et al. (2010) studied this question.
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