Population
Swine carotid medial strips
Design
Preclinical
Authors
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Supports dephosphorylation as key to vascular relaxation in animal models; leaves open translation to human therapeutics.
The study provides preclinical evidence that Ca2+-dependent cross-bridge dephosphorylation is necessary and sufficient to explain relaxation in vascular smooth muscle.
Hai et al. (1989) studied this question.
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