Why the study?
Do elevated serotonin levels predict the occurrence of the no-reflow phenomenon in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention?
Population
40 patients with acute myocardial infarction admitted within 12 hours of chest pain onset who underwent…
Comparison
Measurement of serotonin levels from blood… vs Patients with normal post-procedure flow versus…
Design
Cross-sectional
Authors
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Serum serotonin levels do not predict no-reflow; hypothesis-generating for other mediators in primary PCI patients.
Do elevated serotonin levels predict the occurrence of the no-reflow phenomenon in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention?
Coronary ostial serotonin levels measured prior to primary PCI do not appear to be significantly associated with the development of the no-reflow phenomenon in patients with acute myocardial infarction.
Topsakal et al. (2010) studied this question.
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