Why the study?
Does nefazodone compared to imipramine and placebo affect highway driving, cognitive functions, and daytime sleepiness in healthy subjects?
Does nefazodone compared to imipramine and placebo affect highway driving, cognitive functions, and daytime sleepiness in healthy subjects?
Nefazodone at 200 mg twice daily, but not 100 mg, causes slight impairment in driving and cognitive functions after repeated dosing in healthy subjects.
No takes yet. Share an insight, caveat, or question.
Repeated nefazodone dosing impairs driving and cognition in healthy subjects; extends single-dose data but leaves patient effects open.
Laar et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: