Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 13, 2020KardiologiiaOpen Access

Vulnerable plaques had a significantly greater necrotic core (35.1±8.5% vs. 24.0±13.2%; p=0.008) and calcified nodules (2.0% vs. 1.0%; p=0.006) compared to stable plaques, with blood glucose correlating with the lipid component (r=0.48198; p=0.033).

View Full Paper
Ask AI
Bookmark
Share

Why the study?

To identify new predictors for the vulnerability of atherosclerotic coronary plaques in patients with stable ischemic heart disease.

Do indexes of inflammation, dyslipidemia, and carbohydrate metabolism predict coronary plaque vulnerability in patients with stable ischemic heart disease?

Population

58 patients with sIHD

Comparison

Unstable vs stable coronary plaques

Design

Prospective, single-center study

Authors

NKN. А. KocherginАКА. М. КочергинаVGV. I. Ganyukov

Discussion

Loading...

Member takes

Overview

Metabolic indexes correlate with plaque vulnerability in sIHD; leaves open prospective validation before clinical use.

Structured PICO

Do indexes of inflammation, dyslipidemia, and carbohydrate metabolism predict coronary plaque vulnerability in patients with stable ischemic heart disease?

P
Population
58 patients with stable ischemic heart disease (sIHD)
O
Outcome
Vulnerability of atherosclerotic coronary plaques in proximal and medium segments without significant lesions, detected by virtual histology intravascular ultrasoundsurrogate

In patients with stable ischemic heart disease, dyslipidemia and blood glucose levels correlate with specific morphological features of vulnerable coronary plaques as assessed by virtual histology intravascular ultrasound.

Cite This Study

Kochergin et al. (2020) studied this question.

synapsesocial.com/papers/6a702bef3ce530166bc2c141https://doi.org/10.18087/cardio.2020.10.n1188
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Detecting Vulnerable Plaque Using Peripheral Blood:2003 · 36 citations
  2. 2Low Density Lipoprotein-Cholesterol/High Density Lipoprotein-Cholesterol Ratio Predicts Plaque Vulnerability in Patients With Stable Angina2012 · 13 citations
  3. 3Defining “Vulnerable” in coronary artery disease: predisposing factors and preventive measures2025 · 2 citations
  4. 4Linking Lipidomics to Vulnerable Coronary Plaques: A PROSPECT II Substudy2026
  5. 5Features of simple inflammation markers in assessing the plaque vulnerability in patients with acute coronary syndrome2024 · 1 citations