Population
In vitro biochemical model using gelsolin-severed actin fragments
Comparison
Addition of tropomyosin and/or caldesmon vs Gelsolin-severed actin fragments without…
Design
Preclinical
Authors
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May guide research on sarcomere stability; leaves open any cardiovascular therapeutic implications.
Tropomyosin and caldesmon regulate the capping and severing activities of gelsolin, promoting the annealing of severed actin filaments.
Ishikawa et al. (1989) studied this question.
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