Why the study?
Research describing fetal arterial structure and function is lacking within the literature.
Does maternal diabetes affect fetal abdominal aorta IMT, compliance, and distensibility measured by ultrasonography?
Does maternal diabetes affect fetal abdominal aorta IMT, compliance, and distensibility measured by ultrasonography?
This study demonstrates the feasibility of measuring fetal abdominal aorta biometrics and biomechanical characteristics using conventional ultrasonography, revealing increased compliance in fetuses of diabetic mothers.
No differences in fetal aortic IMT or distensibility by maternal diabetes; leaves open timing of vascular changes in diabetic pregnancies.
Research describing fetal arterial structure and function is lacking within the literature. This study's purpose was to measure intima-media thickness (IMT), compliance and distensibility of 24- to 25-week fetuses' abdominal aortas using conventional ultrasonography from 16 diabetic (DM) and 25 non-diabetic mothers (NDM). We found no significant differences in fetal abdominal aorta IMT (P = .68), diameter distensibility (P = .22), or cross-sectional distensibility (P = .23). However, both fetal abdominal aortic diameter compliance (P = .03) and cross-sectional compliance (P = .005) were greater in DM than in NDM (P = .005). This study demonstrates that it is possible and potentially useful to measure fetal abdominal aorta biometrics and biomechanical characteristics.
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Evanoff et al. (2020) studied this question.
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