Calcium-dependent regulator protein: Localization in mitotic apparatus of eukaryotic cells
Population
Eukaryotic cells
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Hypothesis-generating for calcium's role in chromosome movement; leaves open functional validation in mammalian cells.
Structured PICO
P
Population
Eukaryotic cells
I
Intervention
Indirect immunofluorescence to investigate protein distribution during mitosis
O
Outcome
Distribution and localization of the calcium-dependent regulator protein during mitosis
The distinct localization of calcium-dependent regulator protein during mitosis suggests it may mediate calcium effects on the mitotic apparatus and play a role in chromosome movement.
Cite This Study
Welsh et al. (1978) studied this question.