Why the study?
Does fetal ECG ST waveform analysis identify fetuses at risk of hypoxia and acidosis during labor?
Does fetal ECG ST waveform analysis identify fetuses at risk of hypoxia and acidosis during labor?
Fetal ECG ST waveform analysis (T/QRS ratio) during labor is highly sensitive for identifying fetal hypoxia and acidosis, and its specificity is improved when combined with fetal heart rate monitoring.
Supports T/QRS monitoring as a sensitive marker in labor; observational data leave open its impact on outcomes before practice change.
Fetal heart rate (FHR) and fetal electrocardiogram (ECG) recordings were obtained from a scalp electrode with maternal thigh as reference and used for ST waveform analysis in 201 patients in labour. Nearly 45% had suspicious or abnormal FHR traces whilst only 27% had T/QRS ratio greater than 0.25 (mean +/- 2 SD). A normal T/QRS ratio identified 99.3% of fetuses with normal buffering capacity in cord artery blood. Of 13 infants with a cord artery blood pH less than 7.15, standard bicarbonate was less than 15.0 mmol/l in five who had an average T/QRS ratio less than 0.25 throughout labour. Of the eight with respiratory acidosis, five had an increase in T/QRS ratio greater than 0.25 for longer than 20 minutes prior to delivery, in two the ratio increased during the last few minutes and one had no change (pH 7.14). Persistent elevation of T/QRS in the first stage of labour identified those with decrease in buffer capacity in cord arterial blood (sensitivity of 94.1%). Acute hypoxia was recognized by the rapid rise in T/QRS. The specificity of T/QRS to identify fetuses at risk increased by combining the ST waveform analysis with FHR changes.
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Arulkumaran et al. (1990) studied this question.
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