Population
Cultured mouse adipocytes (adipose 3T3-F442A cells) and rabbits (used to raise polyclonal antibodies)
Design
Preclinical
Authors
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Alerts to underestimated intracellular LPL in adipocyte assays; leaves open in vivo metabolic relevance.
The study demonstrates that intracellular lipoprotein lipase activity in mouse adipocytes is systematically underestimated and exists in a cryptic state that can be unmasked in vitro.
Vannier et al. (1989) studied this question.
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