Why the study?
Does intravenous labetalol reduce blood pressure and alter hormone levels compared to propranolol in hypertensive patients?
Population
20 recumbent hypertensive patients
Comparison
Intravenous labetalol (1-5-2-0 mg/kg) vs Intravenous propranolol 10 mg
Design
Other
Follow-up
up to 24 hours
Authors
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May support IV labetalol for rapid BP reduction in hypertension; leaves open comparative effects versus propranolol pending larger trials.
Does intravenous labetalol reduce blood pressure and alter hormone levels compared to propranolol in hypertensive patients?
Intravenous labetalol effectively lowers blood pressure in hypertensive patients, demonstrating greater blood pressure reduction but less heart rate and angiotensin II reduction compared to intravenous propranolol.
Rosei et al. (1976) studied this question.