January 21, 2010Journal of VirologyOpen Access

Evolutionary Genetics of Human Enterovirus 71: Origin, Population Dynamics, Natural Selection, and Seasonal Periodicity of the VP1 Gene

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Population

Global VP1 capsid sequences of Human enterovirus 71 (n = 628) sampled over 4 decades

Design

Other

Authors

KTKok Keng TeeKunming Medical University TLTommy Tsan‐Yuk LamDepartment of Health YCYoke Fun ChanUniversity of Teramo

Discussion

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Implication

Warrants strengthened genomic surveillance for cryptic EV-71 lineages; leaves open drivers of emergence to guide vaccine design.

Structured PICO

Population

Global VP1 capsid sequences of Human enterovirus 71 (n = 628) sampled over 4 decades

Outcome

Evolutionary dynamics, origin, population dynamics, natural selection, and seasonal periodicity of the VP1 gene

Evolutionary analysis of EV-71 reveals cryptic circulation of lineages prior to outbreaks and temporal strain replacement, informing future vaccine design.

Cite This Study

Tee et al. (2010) studied this question.

synapsesocial.com/papers/6a70334675498292b70995bc https://doi.org/10.1128/jvi.01019-09

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Evolutionary Genetics of Human Enterovirus 71: Origin, Population Dynamics, Natural Selection, and Seasonal Periodicity of the VP1 Gene

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Evolutionary Genetics of Human Enterovirus 71: Origin, Population Dynamics, Natural Selection, and Seasonal Periodicity of the VP1 Gene

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider