Why the study?
Does stage-based management improve clinical outcomes and reduce mortality in pediatric patients with Enterovirus 71 infection?
Population
527 pediatric patients with Enterovirus 71 infection at Chang Gung Children's Hospital, Taiwan.
Comparison
Stage-based management program vs No stage-based management
Design
Cohort
Authors
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May support stage-based management to reduce acute mortality in severe EV71; hypothesis-generating and requires prospective confirmation before practice change.
Does stage-based management improve clinical outcomes and reduce mortality in pediatric patients with Enterovirus 71 infection?
Stage-based management reduces acute mortality in EV71-related cardiopulmonary failure, but a high proportion of survivors experience severe neurological sequelae.
Chang et al. (2004) studied this question.
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