Describes a kindred with late-onset distal myopathy, highlighting the potential for associated cardiomyopathy.
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May suggest cardiomyopathy association in late-onset distal myopathy; hypothesis-generating and should not yet change practice.
A kindred is described in which six members, and probably a seventh, have been affected by a late-onset distal myopathy. Detailed clinical, laboratory, biopsy and autopsy findings are described in two family members. Myopathic histologic changes were observed in numerous biopsy and autopsy muscle specimens. Cardiomyopathy was present in one case.
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Markesbery et al. (1974) studied this question.
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