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April 27, 2011European Journal of Preventive CardiologyOpen Access

Discrepancy between coronary artery calcium score and HeartScore in middle-aged Danes: the DanRisk study

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Why the study?

Does the HeartScore risk model accurately predict the presence of coronary artery calcification in healthy middle-aged individuals?

Population

1,156 healthy middle-aged Danes, 47% men, 53% women, without previous cardiovascular disease or diabetes…

Comparison

Coronary artery calcium score calculation via… vs HeartScore risk model

Design

Cross-sectional

Authors

ADAxel Cosmus Pyndt DiederichsenPreventive CardiologyNSNiels Peter Rønnow SandCardiac ImagingBNBjarne Linde NørgaardCardiac Imaging

Discussion

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Member takes

Overview

HeartScore may misclassify atherosclerotic burden; challenges its accuracy and leaves open whether CAC refines risk prediction.

Structured PICO

Does the HeartScore risk model accurately predict the presence of coronary artery calcification in healthy middle-aged individuals?

P
Population
1,156 healthy middle-aged Danes (50 or 60 years old), 47% men, 53% women, without previous cardiovascular disease or diabetes mellitus.
I
Intervention
Coronary artery calcium (CAC) score calculation via non-contrast enhanced cardiac-CT scan
C
Comparator
HeartScore risk model (10-year risk of fatal cardiovascular events)
O
Outcome
Discrepancy between HeartScore risk classification and presence of coronary artery calcificationsurrogate

There is a significant discrepancy between the HeartScore risk model and CAC scores, suggesting that traditional risk scoring may misclassify actual atherosclerotic burden in middle-aged individuals.

Cite This Study

Diederichsen et al. (2011) studied this question.

synapsesocial.com/papers/6a7033e4e5469ee92be0f3c3https://doi.org/10.1177/1741826711409172
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Also Consider

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  1. 1Prediction of Coronary Heart Disease Using Risk Factor Categories1998 · 9,680 citations
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  5. 5Signs of subclinical coronary atherosclerosis in relation to risk factor distribution in the Multi-Ethnic Study of Atherosclerosis (MESA) and the Heinz Nixdorf Recall Study (HNR)2008 · 69 citations