Why the study?
Does the change in sinus node recovery time after pharmacologic autonomic blockade correlate with disease severity and organic damage in sick sinus syndrome?
Does the change in sinus node recovery time after pharmacologic autonomic blockade correlate with disease severity and organic damage in sick sinus syndrome?
Classification of sick sinus syndrome based on changes in sinus node recovery time before and after pharmacologic autonomic blockade is useful for evaluating the severity of sinus node dysfunction and underlying organic damage.
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May support severity stratification in sick sinus syndrome via autonomic blockade response; hypothesis-generating, needs prospective validation before clinical use.
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Baba et al. (1994) studied this question.
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