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January 1, 2006Journal of Atherosclerosis and ThrombosisOpen Access

Regional Arterial Stiffness Associated with Ischemic Heart Disease in Type 2 Diabetes Mellitus

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Population

595 patients with type 2 diabetes mellitus, including 70 with ischemic heart disease (IHD)

Comparison

Measurement of regional arterial stiffness using… vs Patients with type 2 diabetes mellitus without…

Design

Cross-sectional

Authors

SHSawako HatsudaChubu Rosai HospitalTSTetsuo ShojiVascular MedicineKSKayo ShinoharaPharmaceuticals and Medical Devices Agency

Discussion

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Implication

Central stiffness linked to IHD in T2D; hypothesis-generating and requires prospective validation before clinical use.

Structured PICO

P
Population
595 patients with type 2 diabetes mellitus, including 70 with ischemic heart disease (IHD)
I
Intervention
Measurement of regional arterial stiffness using pulse wave velocity (PWV) in heart-carotid, heart-femoral, heart-brachial, and femoral-ankle regions
C
Comparator
Patients with type 2 diabetes mellitus without ischemic heart disease
O
Outcome
Association between regional arterial stiffness (PWV) and the presence of ischemic heart diseasesurrogate

In patients with type 2 diabetes, increased central arterial stiffness (heart-femoral PWV) is independently associated with the presence of ischemic heart disease.

Cite This Study

Hatsuda et al. (2006) studied this question.

synapsesocial.com/papers/6a7039bcac440176ef28e110https://doi.org/10.5551/jat.13.114

Topics

Women and heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Increased Arterial Wall Stiffness Limits Flow Volume in the Lower Extremities in Type 2 Diabetic Patients2001 · 200 citations
  2. 2Correlation between the intima-media thickness of the carotid artery and aortic pulse-wave velocity in patients with type 2 diabetes. Vessel wall properties in type 2 diabetes.1999 · 284 citations
  3. 3Pulse Wave Velocity in Lower-Limb Arteries among Diabetic Patients with Peripheral Arterial Disease.2003 · 131 citations
  4. 4Stiffness of Capacitive and Conduit Arteries2005 · 407 citations
  5. 5Angiotensin-Converting Enzyme Gene Polymorphism Is Associated With Carotid Arterial Wall Thickness in Non–Insulin-Dependent Diabetic Patients1996 · 99 citations