Why the study?
Does the use of conventional or atypical antipsychotics increase the risk of hospitalization for ventricular arrhythmias or cardiac arrest in nursing home residents?
Population
3,611 nursing home residents in 6 US states, comprising 649 cases hospitalized for ventricular arrhythmias…
Comparison
Conventional and atypical antipsychotics vs Matched controls residing in the same facility
Design
Case-control
Authors
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May warrant caution with conventional antipsychotics in nursing home residents; hypothesis-generating for differential arrhythmic risk versus atypicals.
Does the use of conventional or atypical antipsychotics increase the risk of hospitalization for ventricular arrhythmias or cardiac arrest in nursing home residents?
Conventional, but not atypical, antipsychotics are associated with a significantly increased risk of hospitalization for ventricular arrhythmias and cardiac arrest in nursing home residents.
Liperoti et al. (2005) studied this question.
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