Why the study?
Does ioxaglate compared to iohexol alter clinical, hemodynamic, and electrocardiographic effects in patients undergoing diagnostic cardiac catheterization?
Population
80 patients undergoing diagnostic cardiac catheterization
Comparison
Sodium meglumine ioxaglate vs Iohexol
Design
RCT, randomized, double-blind
Follow-up
two-minute observation period
Authors
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Either agent is acceptable for diagnostic catheterization; confirms substantial hemodynamic equivalence aside from minor heart rate differences.
Does ioxaglate compared to iohexol alter clinical, hemodynamic, and electrocardiographic effects in patients undergoing diagnostic cardiac catheterization?
Ioxaglate and iohexol have substantially similar hemodynamic and electrocardiographic effects during diagnostic cardiac catheterization, with iohexol causing slightly greater transient decreases in heart rate.
Petersen et al. (1992) studied this question.
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