Why the study?
Flavonoids show salutary cardiovascular effects and lower cardiovascular morbidity and mortality, but their specific antihypertensive effects in experimental models needed to be reviewed.
Do flavonoids reduce blood pressure in experimental models of arterial hypertension?
Do flavonoids reduce blood pressure in experimental models of arterial hypertension?
This mini-review highlights the potential antihypertensive effects of flavonoids in experimental models, supporting further investigation into their cardiovascular benefits.
Epidemiological links between dietary flavonols/flavones and lower CVD mortality leave open causal effects in hypertension.
Flavonoids are a class of substances of a vegetal origin with many interesting actions from the point of view of human disease. Interest in flavonoids in the diet has increased in recent years due to the publication of basic, clinical and epidemiological studies that have shown a whole array of salutary effects related to intake of flavonols and flavones as well as a lower morbility and mortality of cardiovascular diseases. Since arterial hypertension is the most common modifiable risk factor for cardiovascular diseases, this review will focus mainly on the effects of flavonoids on the cardiovascular system with relation to the elevation of blood pressure. Its antihypertensive effects as well as the many investigations performed in experimental models of arterial hypertension, are reviewed in this mini-review.
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Atuchá et al. (2021) studied this question.
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