Population
Post-myocardial infarction (MI) setting (review of left ventricular remodeling)
Design
Review
Authors
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Does not support MMP/TIMP modulation in post-MI care; leaves open phase-specific targeting for future remodeling trials.
Understanding the spatiotemporal roles of MMPs and TIMPs post-MI may provide insight into novel therapeutic targets to limit adverse left ventricular remodeling.
Lindsey et al. (2010) studied this question.
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