September 12, 2018American Journal of Roentgenology

Can Adrenal Adenomas Be Differentiated From Adrenal Metastases at Single-Phase Contrast-Enhanced CT?

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Why the study?

Can single-phase contrast-enhanced CT reliably differentiate adrenal metastases from adenomas in patients with lung cancer?

Structured PICO

Can single-phase contrast-enhanced CT reliably differentiate adrenal metastases from adenomas in patients with lung cancer?

Population

61 consecutive patients from a single-institution lung cancer registry with 76 adrenal lesions (40 metastases and 36 adenomas)

Intervention

Single-phase contrast-enhanced CT

Outcome

Differentiation of adrenal metastases from adenomas based on CT features (smooth margin, rim enhancement, central vein sign, homogeneity, size, attenuation, and quantitative texture analysis)surrogate

Single-phase contrast-enhanced CT cannot reliably differentiate adrenal metastases from adenomas due to unacceptably low sensitivity, despite high specificity for heterogeneity.

Discussion

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Implication

Adrenal metastases cannot be reliably distinguished from adenomas on single-phase CT; leaves open the need for multiphase protocols or biopsy confirmation in prospective studies.

Cite This Study

Tu et al. (2018) studied this question.

synapsesocial.com/papers/6a703fc0ac440176ef28e554 https://doi.org/10.2214/ajr.17.19276

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Implication

Adrenal metastases cannot be reliably distinguished from adenomas on single-phase CT; leaves open the need for multiphase protocols or biopsy confirmation in prospective studies.

Can Adrenal Adenomas Be Differentiated From Adrenal Metastases at Single-Phase Contrast-Enhanced CT?

Structured PICO

Discussion

Implication

Cite This Study

Can Adrenal Adenomas Be Differentiated From Adrenal Metastases at Single-Phase Contrast-Enhanced CT?

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider